NEET Biomolecules PYQ practice sheet

20 previous-year NEET Zoology questions from Biomolecules, newest papers first. Biomolecules carries 38 of the Zoology questions in NEET 2020 to 2026, so this is a good place to test yourself after revising the chapter. Marking: +4 correct, −1 wrong.

1. 1.

   RE-NEET 2026

   Match List-I with List-II. List-I: A. Starch B. Antibody C. Concanavalin A D. Glut-4 List-II: I. Fights infection II. Energy storage III. Glucose transport IV. Lectin Choose the correct answer from the options given below :

   • (A)
     A-II, B-I, C-III, D-IV
   • (B)
     A-II, B-I, C-IV, D-III
   • (C)
     A-I, B-II, C-III, D-IV
   • (D)
     A-I, B-II, C-IV, D-III
2. 2.

   RE-NEET 2026

   Arrange the following elements in descending order of their contribution to percentage weight of the human body. (a) Oxygen (b) Carbon (c) Hydrogen (d) Nitrogen Choose the correct answer from the options given below :

   • (A)
     (c), (a), (b), (d)
   • (B)
     (b), (c), (d), (a)
   • (C)
     (a), (b), (c), (d)
   • (D)
     (b), (a), (c), (d)
3. 3.

   NEET 2026

   Alpha-helix is found in which level of protein structure?

   • (A)
     Tertiary structure
   • (B)
     Secondary structure
   • (C)
     Primary structure
   • (D)
     Quaternary structure
4. 4.

   NEET 2026

   Identify the correct statements about biomolecules. A. Lipids are generally water soluble. B. Proteins are polypeptides. C. Polysaccharides are long chains of sugars. D. Adenine and guanine are substituted pyrimidines. E. Almost all enzymes are proteins. Choose the correct answer from the options given below:

   • (A)
     C, D and E only
   • (B)
     A, B and C only
   • (C)
     B, C and E only
   • (D)
     B, D and E only
5. 5.

   NEET 2026

   Which of the following statements are correct regarding amino acids? A. They are substituted methanes. B. Serine is an aromatic amino acid. C. Valine is a neutral amino acid. D. Lysine is an acidic amino acid. Choose the correct answer from the options given below:

   • (A)
     A and C only
   • (B)
     C and D only
   • (C)
     B and C only
   • (D)
     A and B only
6. 6.

   NEET 2026

   Match List I with List II: List I: A. Trypsin, B. Morphine, C. Concanavalin A, D. Collagen List II: I. Intercellular ground substance, II. Lectin, III. Enzyme, IV. Alkaloid Choose the correct answer from the options given below:

   • (A)
     A-IV, B-III, C-II, D-I
   • (B)
     A-III, B-IV, C-II, D-I
   • (C)
     A-I, B-II, C-III, D-IV
   • (D)
     A-III, B-II, C-IV, D-I
7. 7.

   NEET 2026

   The following reaction depicts the activity of a particular class of enzymes:

   $$\begin{array}{c}\mathrm{X\quad\ \ Y}\\ \mathrm{|\qquad\ \ |}\\ \mathrm{C-C}\end{array}\ \xrightarrow{\ E\ }\ \mathrm{X-Y}+\mathrm{C=C}$$

   (Substrate: $\mathrm{X}$ and $\mathrm{Y}$ attached to adjacent carbon atoms; Products: $\mathrm{X-Y}$ and a molecule with a $\mathrm{C=C}$ double bond.) Identify the enzymes class 'E' from the following options:

   • (A)
     Lyases
   • (B)
     Isomerases
   • (C)
     Ligases
   • (D)
     Transferases
8. 8.

   NEET 2024

   Inhibition of succinic dehydrogenase enzyme by malonate is a classical example of:

   • (A)
     Cofactor inhibition
   • (B)
     Competitive inhibition
   • (C)
     Feedback inhibition
   • (D)
     Enzyme activation
9. 9.

   NEET 2024

   Lecithin, a small molecular weight organic compound found in living tissues, is an example of:

   • (A)
     Amino acids
   • (B)
     Phospholipids
   • (C)
     Glycerides
   • (D)
     Carbohydrates
10. 10.

    NEET 2024

    The cofactor of the enzyme carboxypeptidase is:

    • (A)
      Niacin
    • (B)
      Flavin
    • (C)
      Zinc
    • (D)
      Haem
11. 11.

    NEET 2024

    Match List-I with List-II. List-I: (A) GLUT-4, (B) Insulin, (C) Trypsin, (D) Collagen List-II: (I) Hormone, (II) Enzyme, (III) Intercellular ground substances, (IV) Enables glucose transport into cell Choose the correct answer from the options given below:

    • (A)
      A-III, B-IV, C-I, D-II
    • (B)
      A-II, B-III, C-IV, D-I
    • (C)
      A-I, B-II, C-III, D-IV
    • (D)
      A-IV, B-I, C-II, D-III
12. 12.

    NEET 2024

    Match List I with List II: List I: A. Lipase, B. Nuclease, C. Protease, D. Amylase List II: I. Peptide bond, II. Ester bond, III. Glycosidic bond, IV. Phosphodiester bond Choose the correct answer from the options given below:

    • (A)
      A-IV, B-II, C-III, D-I
    • (B)
      A-III, B-II, C-I, D-IV
    • (C)
      A-IV, B-I, C-III, D-II
    • (D)
      A-II, B-IV, C-I, D-III
13. 13.

    NEET 2024

    Regarding catalytic cycle of an enzyme action, select the correct sequential steps: A. Substrate enzyme complex formation. B. Free enzyme ready to bind with another substrate. C. Release of products. D. Chemical bonds of the substrate broken. E. Substrate binding to active site. Choose the correct answer from the options given below:

    • (A)
      B, A, C, D, E
    • (B)
      A, E, B, D, C
    • (C)
      E, A, D, C, B
    • (D)
      E, D, C, B, A
14. 14.

    NEET 2023

    Cellulose does not form blue colour with Iodine because

    • (A)
      It breakes down when iodine reacts with it.
    • (B)
      It is a disaccharide.
    • (C)
      It is a helical molecule.
    • (D)
      It does not contain complex helices and hence cannot hold iodine molecules.
15. 15.

    NEET 2023

    Melonate inhibits the growth of pathogenic bacteria by inhibiting the activity of

    • (A)
      Dinitrogenase
    • (B)
      Succinic dehydrogenase
    • (C)
      Amylase
    • (D)
      Lipase
16. 16.

    NEET 2023

    Given below are two statements: Statement I: A protein is imagined as a line, the left end represented by first amino acid (C-terminal) and the right end represented by last amino acid (N-terminal). Statement II: Adult human haemoglobin, consists of 4 subunits (two subunits of $\alpha$ type and two subunits of $\beta$ type.) In the light of the above statements, choose the correct answer from the options given below:

    • (A)
      Statement I is false but Statement II is true.
    • (B)
      Both Statement I and Statement II are true.
    • (C)
      Both Statement I and Statement II are false.
    • (D)
      Statement I is true but Statement II is false.
17. 17.

    NEET 2023

    Given below are two statements: Statement I: Low temperature preserves the enzyme in a temporarily inactive state whereas high temperature destroys enzymatic activity because proteins are denatured by heat. Statement II: When the inhibitor closely resembles the substrate in its molecular structure and inhibits the activity of the enzyme, it is known as competitive inhibitor. In the light of the above statements, choose the correct answer from the options given below:

    • (A)
      Statement I is false but Statement II is true.
    • (B)
      Both Statement I and Statement II are true.
    • (C)
      Both Statement I and Statement II are false.
    • (D)
      Statement I is true but Statement II is false.
18. 18.

    NEET 2022

    A dehydration reaction links two glucose molecules to produce maltose. If the formula for glucose is $\mathrm{C_6H_{12}O_6}$, what is the molecular formula for maltose? (Answer encoded as a single number for the subscript pattern $\mathrm{C_{12}H_xO_{11}}$; enter the value of x.)

    Numerical answer

19. 19.

    NEET 2022

    Match List - I with List - II. List - I (Biological Molecules) (a) Glycogen (b) Globulin (c) Steroids (d) Thrombin List - II (Biological functions) (i) Hormone (ii) Biocatalyst (iii) Antibody (iv) Storage product Choose the correct answer from the options given below:

    • (A)
      (a)-(iv), (b)-(iii), (c)-(i), (d)-(ii)
    • (B)
      (a)-(iii), (b)-(ii), (c)-(iv), (d)-(i)
    • (C)
      (a)-(iv), (b)-(ii), (c)-(i), (d)-(iii)
    • (D)
      (a)-(ii), (b)-(iv), (c)-(iii), (d)-(i)
20. 20.

    NEET 2021

    Which of the following are not secondary metabolites in plants ?

    • (A)
      Morphine, codeine
    • (B)
      Amino acids, glucose
    • (C)
      Rubber, gums
    • (D)
      Vinblastin, curcumin